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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f99562fba91365bb8ab4d33424912f4fe245705d4667334ec7e7f0a46113e8' 
  AND token = '9/P6w/pn50xZqPCXIHOeQMFaDrkPEb3bowPhAolC2I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}