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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d5be5ab8c2b320c7a1629f59714e0a0433e770116386e8156a352163902e31' 
  AND token = 'vBXWQZwvQY5cn9RKSlyDe+1Ru175Ip37XiPoeGH9XbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}