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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2d8e5ba9567445e79740d19b80036fde8f4f07adad8514522a1707e90cb83b3' 
  AND token = '0iCiq6SpwHtwyka5FV1Yl6sIqAkpw8rAiZgHvvRJJic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}