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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443a917323272bdb2b4b10fe3d75965dfc0d8418ab0442843b9f34b6f38559d4' 
  AND token = 'FrDWHl++sLXF9JBR8OkdICsCyQxTduT2LlH13gL9YzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}