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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b60319735de31d9023dd1fd0142dbbc7c445b249cccf1c3c9688ca26d5654ce' 
  AND token = 'pR7k0SU0kUWT1SwWwnDMKZB/UCPfuZgECNZyZddFM98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}