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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8543831128e420ca2d929ed8858d4a8153ae3a4f3cf614895901326c93483914' 
  AND token = 'JE/+9n1JcvaZDyd3tFwPiVC3oa+1Dy2HS8Qwn6RDHyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}