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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e178426e7d4a99b8c5d7fb7f117aa9087962d5af01d8b434f53fc9376e8e78' 
  AND token = 'qAVLRMPj4IkSS47kU+t1d4yjd/DAPb8aFk5XRSclf7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}