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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21b414b59e0422f859eaf8b404ec10ec98e805f12356bef8a62fd3470be8d99' 
  AND token = 'iKhRSxdfphuj1S+BA1JWiRvLFsHEwqfPXvfFKEEdnC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}