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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f34d82d025ab371a17030673467b982e4e138ecdb6532017547dc4af23b70e1c' 
  AND token = 'kF2UJB1Lfdn9aY0LWAurQezsdc5KM6sqhfw9iL1kiYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}