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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd942bd348d3ba47638e3e28c858e15a7c3e9132c45ec91f4bc8851a8623a1242' 
  AND token = 'hsJSFGdT+UTYiIeKDj5SGIvM0oldAv0j3NRizGVzX0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}