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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4e091de3da5e4329f83ec6a796cab61976b0fe7051e1787bf0a70a2f62b197' 
  AND token = 'IBisCZOgBSCVw6pjTksln6Q6//CuXd907thnqtdVUDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}