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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3e485b36cf425841c8564b87f4fc59b7010ee5bb38e7b0c50ef96669240cc0' 
  AND token = '0irhInrMXEMvaopSay82mHo9WI9ZyxQw9/Ys20Tyww4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}