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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db22c96228ed3fa3ec99fa36ee313b0eacb760882850ef150bf1729460fe6d1' 
  AND token = 'o2Ic12tEnVuMwzQSsR1FejhTMV2v9EEs6Wm9pG8OJp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}