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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac6f777370c472fedc1c18ac7740416be82c1d5d1ffbf0edce497f9b9d2f0c8d' 
  AND token = '7Kh5Ll/tLV+Da0A6lK5L+2wCHc03SUpH++3UCNAkjI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}