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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c3a8c4a11711550e1b82a247100d0a8598a52474ff98cf73d86f04f43e2a9a' 
  AND token = 'mMmKTGGuEOMs7gCHThkj4YADAzcK4+eIqWqMzGy/W4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}