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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca593d170077af20f019521cbe864b554ff3d0d8ac0b9cfe259c9873639603d5' 
  AND token = 'r8tZpqDqSkmPift0x4EL0w1pzksNm/9lG7dcUYyMOYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}