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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cdd4dd646b608e8669a31c995c5da19535a0850452bfb77beb5e7eae3a742b4' 
  AND token = '+R0TZjrxYweY3eyE0AnIrbraWi+UPcoc/y1wHv+En5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}