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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd8967e2c7d3e24daf1f34b38bc17830c026df992f6cd54f6a3879180bd0c49' 
  AND token = 'm8R0ms7V4sef72FTxwM63lqShH1LZdgQE9dd1LKaVAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}