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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd09c35ad1a5cb6b541bbdabdaf0e4c258ef2f4b04294f08300e9be69eae59b04' 
  AND token = 'qzqvQBpFrHzcYgAdSeWWejrTnNo3v0LULqSSIHA+K2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}