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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e0168da3fac940ddf96a31aba7391ffcc8858cbff3ce3aa1f02af11d601f0a' 
  AND token = 'VP4BtZJGvowozcSf+Qk+i0XV3UF5KG/ZUABJqv/TvdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}