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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc42899e02f78f87a0698f550a0e2420f6fd1abdd5a0ea6119a9e782ac1a91f' 
  AND token = 'JB1SjolCFF+RuW9G8WXX/eoBk64BkSltZhTG4U9OmPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}