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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5a248d9c3d5c5c3b8dc3541447bfc90644fc3fc740dab6ec523d81473ba928' 
  AND token = '5zEdT/V8pxWhJiVY63r3R/RwGiCEdedmiipSs2+zHls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}