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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab479d7f86970673c065eda686bc4437b714ebc8f050e0c563e44a951011ae89' 
  AND token = 'UU0kVXG5xTGlCLrh/9clAMqJTtvFDJPIoD82XFDdtFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}