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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd99a4b00d795288f293c8708c0ce837b02aa1d61c08bb38b48b8bb8c37571349' 
  AND token = 'XKC5TrVBcqNtoR+3u+nkPAZ/InmR36jKwwURdbCr9ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}