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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6518645ef563cef320e7a0b13bf0db7d4423f59594579ea29460856101b749b' 
  AND token = '2dErNxHq+a/kUoJCc5YmDF+QFUkUYTgYNpK9cuDd2cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}