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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e87afc36be7e2ac1d76c38cc2dc94393b8c1792d201fcea72d237a7287b7b1f' 
  AND token = 'YBzOGd7aXAbMTRBbxuoBIExFtC6tKg11heEUJeaTmCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}