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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65eb7bd0e0689505ef19796a3191e7387c5fb5af8fecb5c0b66849cce909639' 
  AND token = 'thYOZUjdywhPiLZ0/GzHtX1ueylKi80g8i/WS87+Yr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}