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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45505204a6d5b762ac09c6792953f26af07768b7eecea25cf0a014db9e3595b' 
  AND token = 'eeXAyrP4US9UZthT+Ue1Ge578cymX6XOZZCsbigO2yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}