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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bdfc24f4223ff5fc901978038aa7428c37b31cb28dfd82d515655e2e1ede6e8' 
  AND token = 'pSxW80ZUZNq5Hg6z5kjiA6L81O3IBk7txV9kEYlPe4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}