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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad952f4d4b47ffd734f028b000af29f17ac021d3583ff5e24580661d7485833' 
  AND token = '9R9ndwhycg09UUV2kZeWpddhuDztyxXE710rs4YSJv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}