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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f647c8cfb64122685d76680400fc6d5f941026321c008e5e895d46f08477cc7' 
  AND token = '9sus36Bh/XNIQC5uzWZAPX1U1EwzWR/bFDAecDDZON0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}