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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86b3d2a19ba258dadbb772fc85892f56224fcf312d9f2373cb857f453ada2c6b' 
  AND token = 'Eap6T/sMgzmobTgHYg84+QJEIziIxcOqUL8sQxRWIRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}