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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d885c72f87312967406cd271fbd057be6d139e44543d7ed00d42b521329b6d' 
  AND token = 'Rw+TCEnx+zJ5fHYRkcK9LoY/qbqMC8IPsDc2NdX4NyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}