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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ca1ca052405bde1f82bf45c67ecc928f1e1ed168c3f27e9a4cb933c65655c4' 
  AND token = 'mkhh89idoBZntjZSqDmeBqTt4T7Qo534kOWSnnfE3bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}