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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b047bfe319db2d0aba706c7818936920346c3345de16f31863561a2c53ba14' 
  AND token = 'zYQT4P6U0HzW+FcCh/6OmR+rT6jcrUwFCotcGO4JrGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}