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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e584a9dbf0da580e7d448041bc02b795e17895fbebea94d7ad72ec7a1d215a' 
  AND token = 'uwRUiuIAgw8wwcYk4kDP9IU4CK4xmHRMLOOKONIgqXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}