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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ab8e675ea66b19ab5684e6a55e42353f1adbb4add96ad9e0c5e3a73dc8a6561' 
  AND token = 'sRCAIhOtydWCzz0wP5g1Jdc4WuqTpnxiE9LZZVDWv8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}