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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65538c551a2a49ddf4d0a5cb97ca6a46c245675b6e047a3c4f16b4017db56445' 
  AND token = 'coFNDSpDEHx/PU0uY88pidNTtMbr2l4Uq95LCu1+Ee0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}