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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3d7e7ba8f9668ccdbe693429b12e38745a097eb1d7f0232dac8a0303a701bc4' 
  AND token = 'PtlR5O/tbGWYx7usRDsUHco36ZfY4c4+Rdok5IukbhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}