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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5edc9770e1c250da31196539a452c8b55223e725c6f1ddc0762eac3a516655b8' 
  AND token = 'HjuyvMN2hMja7Jn8YxAAUHXRvk214oKhAHh3AvaWxUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}