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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ca31d341b0f667c36afdb0e586731fce112636fc40c9a7ce927cfbc3f997b2' 
  AND token = 'EqYI1gLMSZo4dDuof/xUc4ZLG5X7GXvVJ6jECU2tk4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}