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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c9b26ae6a400dc55196981edec80c7d9269bd0876e73e58435c670b426763f6' 
  AND token = 'ThD+XWyatVG0BgV8GwpoutBwzAgnTE+h0cBmTnqn0Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}