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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89a5e1ced5145972e86812575ea8cc4eca0c3bd513014a5a4e93819562780c96' 
  AND token = 'F2h5y7OvtTVSZ0ImsvuKExe6XBTehbzQgVdJyrmgaCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}