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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d7876eeb9f67963f01e5a506d10606e3543b727717f4f8f3481f69f03aa02ea' 
  AND token = 'hW2ntavcpXJR+Q3qcGOrM8zhOCrX4g3E+VgEXV9Vbek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}