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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17468bcc7a31aa4c3916949b297f20bb2c482a3d2e48038a03875f285a99d52f' 
  AND token = '4rIv4LqqX/kxySlrXGHbSwzY64M+c2YHR1rLM4/FYR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00099

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}