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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aa03dfbb38791bfe0e851281352e2343b09c7041b5509a10e6cdc3bf9642ed5' 
  AND token = 'YxOq4/+cx8MP8rJs5YSfB7YbY0/+N1XW/gxooFELCy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}