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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2234b3f25a0bb2eb7656e5d274d0c92080c2477a202e47ebd8db8833b5e6e240' 
  AND token = 'kLwxZnhfJfR4PTjfm75Gi+Vmse5fK8fzv/DjseDlLPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}