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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a80c101853069b6a017dad37976d85804b9d01462802d5e6ab103a9af7980a8' 
  AND token = 'XC1NRl31FVAw27BkfwaKjop0unCvnjM18AFDcVKd7Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}