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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18389faa0c13c1192f8e85f68670c45ef9c867eeb93f607a71ffae147d9e5039' 
  AND token = 's1ok2jmV2Fszmitet3kaETj+sghftwjJi32hMehhuv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}