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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746eeb044da3f8f31450eb0fb05b9cde82bbe500bbd6b49bbe285ecc50baa0d8' 
  AND token = 'SuNiAa0FxSrPXJdcuJtcrH0TUmp8zJ4732+3TmdD5Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}